Clinical, functional and radiographic consequences of achieving stable low disease activity and remission with adalimumab plus methotrexate or methotrexate alone in early rheumatoid arthritis: 26-week results from the randomised, controlled OPTIMA study

OBJECTIVE: To assess the efficacy and safety of adalimumab plus methotrexate (ADA+MTX) compared with methotrexate monotherapy in achieving stable low disease activity (LDA; disease activity score (DAS28(CRP)) <3.2 at weeks 22 and 26) and clinical, radiographic and functional outcomes in methotrex...

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Detalhes bibliográficos
Main Authors: Kavanaugh, Arthur, Fleischmann, Roy M, Emery, Paul, Kupper, Hartmut, Redden, Laura, Guerette, Benoit, Santra, Sourav, Smolen, Josef S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2013
Assuntos:
Clinical and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551224/
https://ncbi.nlm.nih.gov/pubmed/22562973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2011-201247
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