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Modification of the apolipoprotein B gene in HepG2 cells by gene targeting.
The HepG2 cell line has been used extensively to study the synthesis and secretion of apolipoprotein (apo) B. In this study, we tested whether gene-targeting techniques can be used to inactivate one of the apo B alleles in HepG2 cells by homologous recombination using a transfected gene-targeting ve...
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| Publicado en: | J Clin Invest |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1992
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443089/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115845 |
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