Modification of the apolipoprotein B gene in HepG2 cells by gene targeting.

Por Farese, R V, Flynn, L M, Young, S G
Publicado em 1992

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.

Por Farese, R V, Ruland, S L, Flynn, L M, Stokowski, R P, Young, S G
Publicado em 1995

Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a).

Por McCormick, S P, Ng, J K, Taylor, S, Flynn, L M, Hammer, R E, Young, S G
Publicado em 1995

Phenotypic analysis of mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.

Por Farese, R V, Véniant, M M, Cham, C M, Flynn, L M, Pierotti, V, Loring, J F, Traber, M, Ruland, S, Stokowski, R S, Huszar, D, Young, S G
Publicado em 1996

Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.

Por Purcell-Huynh, D A, Farese, R V, Johnson, D F, Flynn, L M, Pierotti, V, Newland, D L, Linton, M F, Sanan, D A, Young, S G
Publicado em 1995