Efficacy and safety of alirocumab in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia on maximally tolerated doses of statins: the ODYSSEY COMBO II randomized controlled trial

AIMS: To compare the efficacy [low-density lipoprotein cholesterol (LDL-C) lowering] and safety of alirocumab, a fully human monoclonal antibody to proprotein convertase subtilisin/kexin 9, compared with ezetimibe, as add-on therapy to maximally tolerated statin therapy in high cardiovascular risk p...

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Vydáno v:Eur Heart J
Hlavní autoři: Cannon, Christopher P., Cariou, Bertrand, Blom, Dirk, McKenney, James M., Lorenzato, Christelle, Pordy, Robert, Chaudhari, Umesh, Colhoun, Helen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
FASTTrack Clinical Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430683/
https://ncbi.nlm.nih.gov/pubmed/25687353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv028
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