A Mouse Model Suggests Two Mechanisms for Thyroid Alterations in Infantile Cystinosis: Decreased Thyroglobulin Synthesis Due to Endoplasmic Reticulum Stress/Unfolded Protein Response and Impaired Lysosomal Processing

Lignende værker

• Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model
  af: Gaide Chevronnay, H. P., et al.
  Udgivet: (2016)
• Protection of Cystinotic Mice by Kidney-Specific Megalin Ablation Supports an Endocytosis-Based Mechanism for Nephropathic Cystinosis Progression
  af: Janssens, Virginie, et al.
  Udgivet: (2019)
• Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis
  af: Grieco, Giuseppina, et al.
  Udgivet: (2020)
• Upregulation of the Rab27a-Dependent Trafficking and Secretory Mechanisms Improves Lysosomal Transport, Alleviates Endoplasmic Reticulum Stress, and Reduces Lysosome Overload in Cystinosis
  af: Johnson, Jennifer L., et al.
  Udgivet: (2013)
• Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter
  af: Kalatzis, Vasiliki, et al.
  Udgivet: (2001)