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The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond

Post-translational arginine methylation is responsible for regulation of many biological processes. The protein arginine methyltransferase 5 (PRMT5, also known as Hsl7, Jbp1, Skb1, Capsuleen, or Dart5) is the major enzyme responsible for mono- and symmetric dimethylation of arginine. An expanding li...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Stopa, Nicole, Krebs, Jocelyn E., Shechter, David
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430368/
https://ncbi.nlm.nih.gov/pubmed/25662273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-1847-9
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