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Morphine potentiates LPS-induced autophagy initiation but inhibits autophagosomal maturation through distinct TLR4 dependent and independent pathways
AIM: Opioids are the most prescribed analgesics for moderate and severe pain management; however chronic use impairs host innate immune response and increases susceptibility to infection. Recently, autophagy has been shown to be an innate defense mechanism against bacterial infection. The effect of...
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| 出版年: | Acta Physiol (Oxf) |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4430349/ https://ncbi.nlm.nih.gov/pubmed/25850855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12506 |
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