Identification of a thermolabile component of the human neutrophil NADPH oxidase. A model for chronic granulomatous disease caused by deficiency of the p67-phox cytosolic component.

Mild heating of human neutrophils inactivates the respiratory burst oxidase, producing a defect in superoxide production and bacterial killing comparable to that seen in patients afflicted with chronic granulomatous disease (CGD). We have now investigated the mechanism and specificity of this inacti...

Descripción completa

Detalles Bibliográficos

Publicado en:	J Clin Invest
Autores principales:	Erickson, R W, Malawista, S E, Garrett, M C, Van Blaricom, G, Leto, T L, Curnutte, J T
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1992
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1314852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115753
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!