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Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques.

Lipoprotein lipase (LPL), hydrolyzes the core triglycerides of lipoproteins, thereby playing a role in their maturation. LPL may be important in the metabolic pathways that lead to atherosclerosis, since it is secreted in vitro by both of the predominant cell types of the atherosclerotic plaque, i.e...

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Pubblicato in:J Clin Invest
Autori principali: O'Brien, K D, Gordon, D, Deeb, S, Ferguson, M, Chait, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443027/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569193/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115747
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