Parathyroid hormone decreases HCO3 reabsorption in the rat proximal tubule by stimulating phosphatidylinositol metabolism and inhibiting base exit.

The mechanism of inhibition of HCO3 transport by parathyroid hormone (PTH) in the proximal tubule is not clearly defined. Previous studies in vitro have suggested that this effect is mediated via cAMP generation, which acts to inhibit Na/H exchange, resulting in cell acidification. To examine this q...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Pastoriza-Munoz, E, Harrington, R M, Graber, M L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1314850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115739
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