DNase I hypersensitivity analysis of the mouse brain and retina identifies region-specific regulatory elements

BACKGROUND: The brain, spinal cord, and neural retina comprise the central nervous system (CNS) of vertebrates. Understanding the regulatory mechanisms that underlie the enormous cell-type diversity of the CNS is a significant challenge. Whole-genome mapping of DNase I-hypersensitive sites (DHSs) ha...

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Bibliographic Details
Published in:Epigenetics Chromatin
Main Authors: Wilken, Matthew S, Brzezinski, Joseph A, La Torre, Anna, Siebenthall, Kyle, Thurman, Robert, Sabo, Peter, Sandstrom, Richard S, Vierstra, Jeff, Canfield, Theresa K, Hansen, R Scott, Bender, Michael A, Stamatoyannopoulos, John, Reh, Thomas A
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429822/
https://ncbi.nlm.nih.gov/pubmed/25972927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-8-8
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