Reduced ability of C-type natriuretic peptide (CNP) to activate natriuretic peptide receptor B (NPR-B) causes dwarfism in lbab(−/−) mice

C-type natriuretic peptide (CNP) stimulates endochondrial ossification by activating the transmembrane guanylyl cyclase, natriuretic peptide receptor-B (NPR-B). Recently, a spontaneous autosomal recessive mutation that causes severe dwarfism in mice was identified. The mutant, called long bone abnor...

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Publicado en:Peptides
Main Authors: Yoder, Andrea R., Kruse, Andrew C., Earhart, Cathleen A., Ohlendorf, Douglas H., Potter, Lincoln R.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429774/
https://ncbi.nlm.nih.gov/pubmed/18554750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2008.04.020
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