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Coenzyme A sequestration in rat hearts oxidizing ketone bodies.

Previous studies have indicated that ketone body-mediated contractile failure in rat hearts is due to inhibition of 2-oxoglutarate dehydrogenase, and it has been speculated that this inhibition is due to the sequestration of intramitochondrial CoA as acetoacetyl-CoA and acetyl-CoA. These studies wer...

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Détails bibliographiques
Auteurs principaux: Russell, R R, Taegtmeyer, H
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC442945/
https://ncbi.nlm.nih.gov/pubmed/1541685
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