NF-κB induces miR-148a to sustain TGF-β/Smad signaling activation in glioblastoma

BACKGROUND: Inflammatory cytokines and transforming growth factor-β (TGF-β) are mutually inhibitory. However, hyperactivation of nuclear factor-κB (NF-κB) and TGF-β signaling both emerge in glioblastoma. Here, we report microRNA-148a (miR-148a) overexpression in glioblastoma and that miR-148a direct...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Wang, Hui, Pan, Jian-Qing, Luo, Lun, Ning, Xin-jie, Ye, Zhuo-Peng, Yu, Zhe, Li, Wen-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429406/
https://ncbi.nlm.nih.gov/pubmed/25971746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-14-2
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