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Palmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity

Precise regulation of the dendritic spine actin cytoskeleton is critical for neurodevelopment and neuronal plasticity, but how neurons spatially control actin dynamics is not well defined. Here, we identify direct palmitoylation of the actin regulator LIM kinase-1 (LIMK1) as a novel mechanism to con...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: George, Joju, Soares, Cary, Montersino, Audrey, Beique, Jean-Claude, Thomas, Gareth M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429338/
https://ncbi.nlm.nih.gov/pubmed/25884247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06327
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