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Palmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity

Precise regulation of the dendritic spine actin cytoskeleton is critical for neurodevelopment and neuronal plasticity, but how neurons spatially control actin dynamics is not well defined. Here, we identify direct palmitoylation of the actin regulator LIM kinase-1 (LIMK1) as a novel mechanism to con...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: George, Joju, Soares, Cary, Montersino, Audrey, Beique, Jean-Claude, Thomas, Gareth M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429338/
https://ncbi.nlm.nih.gov/pubmed/25884247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06327
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