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Palmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity
Precise regulation of the dendritic spine actin cytoskeleton is critical for neurodevelopment and neuronal plasticity, but how neurons spatially control actin dynamics is not well defined. Here, we identify direct palmitoylation of the actin regulator LIM kinase-1 (LIMK1) as a novel mechanism to con...
Gorde:
Argitaratua izan da: | eLife |
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Egile Nagusiak: | , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
eLife Sciences Publications, Ltd
2015
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4429338/ https://ncbi.nlm.nih.gov/pubmed/25884247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06327 |
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