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Modeling drug resistance in a conjoint normal-tumor setting

BACKGROUND: In this paper, we modify our previously developed conjoint tumor-normal cell model in order to make a distinction between tumor cells that are responsive to chemotherapy and those that may show resistance. RESULTS: Using this newly developed core model, the evolution of three cell types:...

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Detalhes bibliográficos
Publicado no:Theor Biol Med Model
Main Authors: Feizabadi, Mitra Shojania, Witten, Tarynn M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429337/
https://ncbi.nlm.nih.gov/pubmed/25588472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-12-3
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