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Modeling multi-mutation and drug resistance: analysis of some case studies

BACKGROUND: Drug-induced resistance is one the major obstacles that may lead to therapeutic failure during cancer treatment. Different genetic alterations occur when tumor cells divide. Among new generations of tumor cells, some may express intrinsic resistance to a specific chemotherapeutic agent....

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Detalhes bibliográficos
Publicado no:Theor Biol Med Model
Autor principal: Feizabadi, Mitra Shojania
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361792/
https://ncbi.nlm.nih.gov/pubmed/28327183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12976-017-0052-y
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