Liver-specific deletion of Ppp2cα enhances glucose metabolism and insulin sensitivity

Protein phosphatase 2A (PP2A) is a key negative regulator of phosphatidylinositol 3-kinase/Akt pathway. Previous study showed that, in the liver, the catalytic subunit of PP2A (PP2Ac) is closely associated with insulin resistance syndrome, which is characterized by glucose intolerance and dyslipidem...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Xian, Li, Hou, Siyuan, Huang, Zan, Tang, An, Shi, Peiliang, Wang, Qinghua, Song, Anying, Jiang, Shujun, Lin, Zhaoyu, Guo, Shiying, Gao, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429087/
https://ncbi.nlm.nih.gov/pubmed/25888638
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