Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia.

The p53 gene was examined in primary lymphoblasts of 25 pediatric patients with acute lymphoblastic leukemia by the RNase protection assay and by single strand conformation polymorphism analysis in 23 of 25 cases. p53 mutations were found to occur, but at a low frequency (4 of 25). While all four mu...

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Bibliografske podrobnosti
Main Authors: Felix, C A, Nau, M M, Takahashi, T, Mitsudomi, T, Chiba, I, Poplack, D G, Reaman, G H, Cole, D E, Letterio, J J, Whang-Peng, J
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC442897/
https://ncbi.nlm.nih.gov/pubmed/1737852
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