Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa

Patients with recessive dystrophic epidermolysis bullosa (RDEB) lack functional type VII collagen owing to mutations in the gene COL7A1 and suffer severe blistering and chronic wounds that ultimately lead to infection and development of lethal squamous cell carcinoma. The discovery of induced plurip...

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Publicado no:Sci Transl Med
Main Authors: Sebastiano, Vittorio, Zhen, Hanson Hui, Haddad, Bahareh, Bashkirova, Elizaveta, Melo, Sandra P., Wang, Pei, Leung, Thomas L., Siprashvili, Zurab, Tichy, Andrea, Li, Jiang, Ameen, Mohammed, Hawkins, John, Lee, Susie, Li, Lingjie, Schwertschkow, Aaron, Bauer, Gerhard, Lisowski, Leszek, Kay, Mark A., Kim, Seung K., Lane, Alfred T., Wernig, Marius, Oro, Anthony E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428910/
https://ncbi.nlm.nih.gov/pubmed/25429056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009540
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