Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa

Patients with recessive dystrophic epidermolysis bullosa (RDEB) lack functional type VII collagen owing to mutations in the gene COL7A1 and suffer severe blistering and chronic wounds that ultimately lead to infection and development of lethal squamous cell carcinoma. The discovery of induced plurip...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Transl Med
Prif Awduron: Sebastiano, Vittorio, Zhen, Hanson Hui, Haddad, Bahareh, Bashkirova, Elizaveta, Melo, Sandra P., Wang, Pei, Leung, Thomas L., Siprashvili, Zurab, Tichy, Andrea, Li, Jiang, Ameen, Mohammed, Hawkins, John, Lee, Susie, Li, Lingjie, Schwertschkow, Aaron, Bauer, Gerhard, Lisowski, Leszek, Kay, Mark A., Kim, Seung K., Lane, Alfred T., Wernig, Marius, Oro, Anthony E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428910/
https://ncbi.nlm.nih.gov/pubmed/25429056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009540
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