Human cytomegalovirus-stimulated peripheral blood mononuclear cells induce HIV-1 replication via a tumor necrosis factor-alpha-mediated mechanism.

Human cytomegalovirus (HCMV) is a potential cofactor in HIV-1 infection. To investigate the mechanism whereby HCMV promotes HIV-1 replication, a PBMC coculture assay which measures HIV-1 p24 antigen release was used as an index of viral replication. HCMV-stimulated PBMC were capable of inducing HIV-...

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Pubblicato in:	J Clin Invest
Autori principali:	Peterson, P K, Gekker, G, Chao, C C, Hu, S X, Edelman, C, Balfour, H H, Verhoef, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115623
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