Human cytomegalovirus-stimulated peripheral blood mononuclear cells induce HIV-1 replication via a tumor necrosis factor-alpha-mediated mechanism.

Human cytomegalovirus (HCMV) is a potential cofactor in HIV-1 infection. To investigate the mechanism whereby HCMV promotes HIV-1 replication, a PBMC coculture assay which measures HIV-1 p24 antigen release was used as an index of viral replication. HCMV-stimulated PBMC were capable of inducing HIV-...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Peterson, P K, Gekker, G, Chao, C C, Hu, S X, Edelman, C, Balfour, H H, Verhoef, J
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC442890/
https://ncbi.nlm.nih.gov/pubmed/1310698
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