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Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development
The anti-invasive and anti-proliferative effects of betulins and abietane derivatives was systematically tested using an organotypic model system of advanced, castration-resistant prostate cancers. A preliminary screen of the initial set of 93 compounds was performed in two-dimensional (2D) growth c...
Shranjeno v:
izdano v: | PLoS One |
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Main Authors: | , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428838/ https://ncbi.nlm.nih.gov/pubmed/25965345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126111 |
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