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Wide-scale quantitative phosphoproteomic analysis reveals that cold treatment of T cells closely mimics soluble antibody stimulation

The activation of T-lymphocytes through antigen-mediated T-cell receptor (TCR) clustering is vital in regulating the adaptive-immune response. Although T cell receptor signaling has been extensively studied, the fundamental mechanisms for signal initiation are not fully understood. Reduced temperatu...

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Библиографические подробности
Опубликовано в: :J Proteome Res
Главные авторы: Ji, Qinqin, Salomon, Arthur R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428545/
https://ncbi.nlm.nih.gov/pubmed/25839225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr501172u
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