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Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators

Biologically active proteins without stable tertiary structure are common in all known proteomes. Functions of these intrinsically disordered proteins (IDPs) are typically related to regulation, signaling, and control. Cellular levels of these important regulators are tightly regulated by a variety...

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Vydáno v:Front Mol Biosci
Hlavní autor: Uversky, Vladimir N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428494/
https://ncbi.nlm.nih.gov/pubmed/25988147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2014.00006
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