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Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators

Biologically active proteins without stable tertiary structure are common in all known proteomes. Functions of these intrinsically disordered proteins (IDPs) are typically related to regulation, signaling, and control. Cellular levels of these important regulators are tightly regulated by a variety...

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Библиографические подробности
Опубликовано в: :Front Mol Biosci
Главный автор: Uversky, Vladimir N.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428494/
https://ncbi.nlm.nih.gov/pubmed/25988147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2014.00006
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