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Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators

Biologically active proteins without stable tertiary structure are common in all known proteomes. Functions of these intrinsically disordered proteins (IDPs) are typically related to regulation, signaling, and control. Cellular levels of these important regulators are tightly regulated by a variety...

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Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Hovedforfatter: Uversky, Vladimir N.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428494/
https://ncbi.nlm.nih.gov/pubmed/25988147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2014.00006
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