Cysteamine treatment restores the in vitro ability to differentiate along the osteoblastic lineage of mesenchymal stromal cells isolated from bone marrow of a cystinotic patient

BACKGROUND: Cystinosis is a rare autosomal recessive disease caused by mutations of the CTNS gene, which encodes for a lysosomal cystine/H(+) symporter. In mice, inactivation of the CTNS gene causes intralysosomal cystine accumulation and progressive organ damage that can be reversed, at least in pa...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Transl Med
Asıl Yazarlar: Conforti, Antonella, Taranta, Anna, Biagini, Simone, Starc, Nadia, Pitisci, Angela, Bellomo, Francesco, Cirillo, Valentina, Locatelli, Franco, Bernardo, Maria Ester, Emma, Francesco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428230/
https://ncbi.nlm.nih.gov/pubmed/25947233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0494-0
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller