Cysteamine treatment restores the in vitro ability to differentiate along the osteoblastic lineage of mesenchymal stromal cells isolated from bone marrow of a cystinotic patient

BACKGROUND: Cystinosis is a rare autosomal recessive disease caused by mutations of the CTNS gene, which encodes for a lysosomal cystine/H(+) symporter. In mice, inactivation of the CTNS gene causes intralysosomal cystine accumulation and progressive organ damage that can be reversed, at least in pa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Conforti, Antonella, Taranta, Anna, Biagini, Simone, Starc, Nadia, Pitisci, Angela, Bellomo, Francesco, Cirillo, Valentina, Locatelli, Franco, Bernardo, Maria Ester, Emma, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428230/
https://ncbi.nlm.nih.gov/pubmed/25947233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0494-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados