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Effectiveness of Shrinkage and Variable Selection Methods for the Prediction of Complex Human Traits using Data from Distantly Related Individuals

Genome‐wide association studies (GWAS) have detected large numbers of variants associated with complex human traits and diseases. However, the proportion of variance explained by GWAS‐significant single nucleotide polymorphisms has been usually small. This brought interest in the use of whole‐genome...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Hum Genet
Prif Awduron: Berger, Swetlana, Pérez‐Rodríguez, Paulino, Veturi, Yogasudha, Simianer, Henner, de los Campos, Gustavo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428155/
https://ncbi.nlm.nih.gov/pubmed/25600682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12099
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