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Effectiveness of Shrinkage and Variable Selection Methods for the Prediction of Complex Human Traits using Data from Distantly Related Individuals

Genome‐wide association studies (GWAS) have detected large numbers of variants associated with complex human traits and diseases. However, the proportion of variance explained by GWAS‐significant single nucleotide polymorphisms has been usually small. This brought interest in the use of whole‐genome...

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Dettagli Bibliografici
Pubblicato in:Ann Hum Genet
Autori principali: Berger, Swetlana, Pérez‐Rodríguez, Paulino, Veturi, Yogasudha, Simianer, Henner, de los Campos, Gustavo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428155/
https://ncbi.nlm.nih.gov/pubmed/25600682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12099
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