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Effectiveness of Shrinkage and Variable Selection Methods for the Prediction of Complex Human Traits using Data from Distantly Related Individuals

Genome‐wide association studies (GWAS) have detected large numbers of variants associated with complex human traits and diseases. However, the proportion of variance explained by GWAS‐significant single nucleotide polymorphisms has been usually small. This brought interest in the use of whole‐genome...

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Detalhes bibliográficos
Publicado no:Ann Hum Genet
Main Authors: Berger, Swetlana, Pérez‐Rodríguez, Paulino, Veturi, Yogasudha, Simianer, Henner, de los Campos, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428155/
https://ncbi.nlm.nih.gov/pubmed/25600682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12099
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