The thymic cortical epithelium determines the TCR repertoire of IL-17-producing γδT cells

The thymus provides a specialized microenvironment in which distinct subsets of thymic epithelial cells (TECs) support T-cell development. Here, we describe the significance of cortical TECs (cTECs) in T-cell development, using a newly established mouse model of cTEC deficiency. The deficiency of ma...

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Vydáno v:EMBO Rep
Hlavní autoři: Nitta, Takeshi, Muro, Ryunosuke, Shimizu, Yukiko, Nitta, Sachiko, Oda, Hiroyo, Ohte, Yuki, Goto, Motohito, Yanobu-Takanashi, Rieko, Narita, Tomoya, Takayanagi, Hiroshi, Yasuda, Hisataka, Okamura, Tadashi, Murata, Shigeo, Suzuki, Harumi
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428049/
https://ncbi.nlm.nih.gov/pubmed/25770130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540096
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