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Chromosome microduplication in somatic cells decreases the genetic stability of human reprogrammed somatic cells and results in pluripotent stem cells

Human pluripotent stem cells, including cloned embryonic and induced pluripotent stem cells, offer a limitless cellular source for regenerative medicine. However, their derivation efficiency is limited, and a large proportion of cells are arrested during reprogramming. In the current study, we explo...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Yu, Yang, Chang, Liang, Zhao, Hongcui, Li, Rong, Fan, Yong, Qiao, Jie
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428033/
https://ncbi.nlm.nih.gov/pubmed/25965553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10114
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