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Chromosome microduplication in somatic cells decreases the genetic stability of human reprogrammed somatic cells and results in pluripotent stem cells

Human pluripotent stem cells, including cloned embryonic and induced pluripotent stem cells, offer a limitless cellular source for regenerative medicine. However, their derivation efficiency is limited, and a large proportion of cells are arrested during reprogramming. In the current study, we explo...

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Опубликовано в: :Sci Rep
Главные авторы: Yu, Yang, Chang, Liang, Zhao, Hongcui, Li, Rong, Fan, Yong, Qiao, Jie
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428033/
https://ncbi.nlm.nih.gov/pubmed/25965553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10114
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