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Visualizing KcsA Conformational Changes upon Ion Binding by Infrared Spectroscopy and Atomistic Modeling

[Image: see text] The effect of ion binding in the selectivity filter of the potassium channel KcsA is investigated by combining amide I Fourier-transform infrared spectroscopy with structure-based spectral modeling. Experimental difference IR spectra between K(+)-bound KcsA and Na(+)-bound KcsA are...

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Detaylı Bibliyografya
Yayımlandı:J Phys Chem B
Asıl Yazarlar: Stevenson, Paul, Götz, Christoph, Baiz, Carlos R., Akerboom, Jasper, Tokmakoff, Andrei, Vaziri, Alipasha
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2015
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428008/
https://ncbi.nlm.nih.gov/pubmed/25861001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b02223
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