The protein phosphatase activity of PTEN is essential for regulating neural stem cell differentiation

BACKGROUND: The tumor suppressor gene Phosphatase and tensin homolog (PTEN) is highly expressed in neural progenitor cells (NPCs) and plays an important role in development of the central nervous system. As a dual-specificity phosphatase, the loss of PTEN phosphatase activity has been linked to vari...

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Dettagli Bibliografici
Pubblicato in:Mol Brain
Autori principali: Lyu, Jingwen, Yu, Xiuya, He, Lingjie, Cheng, Tianlin, Zhou, Jingjing, Cheng, Cheng, Chen, Zhifang, Cheng, Guoqiang, Qiu, Zilong, Zhou, Wenhao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427940/
https://ncbi.nlm.nih.gov/pubmed/25927309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0114-1
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