Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes.

In inflammatory diseases such as rheumatoid arthritis, functions of chondrocytes including synthesis of matrix proteins and proteinases are altered through interactions with cells of the infiltrating pannus. One of the major secreted products of mononuclear inflammatory cells is IL-1. In this study...

詳細記述

書誌詳細

出版年:	J Clin Invest
主要な著者:	Goldring, M B, Birkhead, J, Sandell, L J, Kimura, T, Krane, S M
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Clinical Investigation 1988
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3264290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113823
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