Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes.

In inflammatory diseases such as rheumatoid arthritis, functions of chondrocytes including synthesis of matrix proteins and proteinases are altered through interactions with cells of the infiltrating pannus. One of the major secreted products of mononuclear inflammatory cells is IL-1. In this study...

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書目詳細資料

發表在:	J Clin Invest
Principais autores:	Goldring, M B, Birkhead, J, Sandell, L J, Kimura, T, Krane, S M
格式:	Artigo
語言:	Inglês
出版:	American Society for Clinical Investigation 1988
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3264290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113823
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