Globular Adiponectin Causes Tolerance to LPS-Induced TNF-α Expression via Autophagy Induction in RAW 264.7 Macrophages: Involvement of SIRT1/FoxO3A Axis

Adiponectin, an adipokine predominantly produced from adipose tissue, exhibited potent anti-inflammatory properties. In particular, it inhibits production of pro-inflammatory cytokines, including tumor necrosis factor-α (TNF-α), in macrophages. Autophagy, an intracellular self-digestion process, has...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Tilija Pun, Nirmala, Subedi, Amit, Kim, Mi Jin, Park, Pil-Hoon
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427353/
https://ncbi.nlm.nih.gov/pubmed/25961287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124636
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