Differential effect of DPI 201-106 on the sensitivity of the myofilaments to Ca2+ in intact and skinned trabeculae from control and myopathic human hearts.

The effects of DPI, a new inotropic agent, were compared in trabeculae carneae from control and myopathic human hearts loaded with aequorin, a bioluminescent calcium indicator that emits light when it combines with calcium, and in saponin-skinned trabeculae carneae from the same hearts. The force-pC...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Hajjar, R J, Gwathmey, J K, Briggs, G M, Morgan, J P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442726/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3183055/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113769
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