Na+ channels as sites of action of the cardioactive agent DPI 201-106 with agonist and antagonist enantiomers.
This paper shows the interaction of the cardiotonic agent 4-[3-(4-diphenylmethyl-1-piperazinyl)-2-hydroxypropoxy]-1H-indole- 2-carbonitrile (DPI 201-106) and its optic enantiomers R-DPI (205-429) and S-DPI (205-430) with the Na+ channel of a variety of excitable cells. Voltage-clamp experiments show...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1987
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304323/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2433694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.3.896 |
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