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Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B–RAGE-derived peptide complex

S100B is a damage-associated molecular pattern protein that, when released into the extracellular milieu, triggers initiation of the inflammatory response through the receptor for advanced glycation end products (RAGE). Recognition of S100B is accomplished via the amino-terminal variable immunoglobu...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Biol Crystallogr
Main Authors: Jensen, Jaime L., Indurthi, Venkata S. K., Neau, David B., Vetter, Stefan W., Colbert, Christopher L.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427201/
https://ncbi.nlm.nih.gov/pubmed/25945582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715004216
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