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Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus

When exposed to high osmolarity, methicillin-resistant Staphylococcus aureus (MRSA) restores its growth and establishes a new steady state by accumulating the osmoprotectant metabolite betaine. Effective osmoregulation has also been implicated in the acquirement of a profound antibiotic resistance b...

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Détails bibliographiques
Publié dans:Acta Crystallogr D Biol Crystallogr
Auteurs principaux: Halavaty, Andrei S., Rich, Rebecca L., Chen, Chao, Joo, Jeong Chan, Minasov, George, Dubrovska, Ievgeniia, Winsor, James R., Myszka, David G., Duban, Mark, Shuvalova, Ludmilla, Yakunin, Alexander F., Anderson, Wayne F.
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427200/
https://ncbi.nlm.nih.gov/pubmed/25945581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715004228
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