Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP

Despite the global medical needs associated with Staphylococcus aureus infections, no licensed vaccines are currently available. We identified and characterized a protein annotated as an epidermin leader peptide processing serine protease (EpiP), as a novel S. aureus vaccine candidate. In addition,...

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Detalhes bibliográficos
Main Authors: Kuhn, Misty L., Prachi, Prachi, Minasov, George, Shuvalova, Ludmilla, Ruan, Jiapeng, Dubrovska, Ievgeniia, Winsor, James, Giraldi, Monica, Biagini, Massimiliano, Liberatori, Sabrina, Savino, Silvana, Bagnoli, Fabio, Anderson, Wayne F., Grandi, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963019/
https://ncbi.nlm.nih.gov/pubmed/24421400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-241737
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