Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers.

Toxin A of Clostridium difficile causes severe inflammatory enterocolitis in man and animals that appears to be mediated in part by acute inflammatory cells that migrate into the toxin A-exposed mucosa. To determine the direct effects of toxin A on intestinal epithelial permeability and structure in...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Hecht, G, Pothoulakis, C, LaMont, J T, Madara, J L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141478/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113760
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