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Structure of uridine diphosphate N-acetylglucosamine pyrophosphorylase from Entamoeba histolytica

Uridine diphosphate N-acetylglucosamine pyrophosphorylase (UAP) catalyzes the final step in the synthesis of UDP-GlcNAc, which is involved in cell-wall biogenesis in plants and fungi and in protein glycosylation. Small-molecule inhibitors have been developed against UAP from Trypanosoma brucei that...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Edwards, Thomas E., Gardberg, Anna S., Phan, Isabelle Q. H., Zhang, Yang, Staker, Bart L., Myler, Peter J., Lorimer, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427165/
https://ncbi.nlm.nih.gov/pubmed/25945709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1500179X
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