An integrative approach to predicting the functional effects of non-coding and coding sequence variation

Motivation: Technological advances have enabled the identification of an increasingly large spectrum of single nucleotide variants within the human genome, many of which may be associated with monogenic disease or complex traits. Here, we propose an integrative approach, named FATHMM-MKL, to predict...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Shihab, Hashem A., Rogers, Mark F., Gough, Julian, Mort, Matthew, Cooper, David N., Day, Ian N. M., Gaunt, Tom R., Campbell, Colin
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Original Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426838/
https://ncbi.nlm.nih.gov/pubmed/25583119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv009
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