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MADGiC: a model-based approach for identifying driver genes in cancer

Motivation: Identifying and prioritizing somatic mutations is an important and challenging area of cancer research that can provide new insights into gene function as well as new targets for drug development. Most methods for prioritizing mutations rely primarily on frequency-based criteria, where a...

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Publicat a:Bioinformatics
Autors principals: Korthauer, Keegan D., Kendziorski, Christina
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426832/
https://ncbi.nlm.nih.gov/pubmed/25573922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu858
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