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SCL/TAL1-mediated Transcriptional Network Enhances Megakaryocytic Specification of Human Embryonic Stem Cells

Human embryonic stem cells (hESCs) are a unique in vitro model for studying human developmental biology and represent a potential source for cell replacement strategies. Platelets can be generated from cord blood progenitors and hESCs; however, the molecular mechanisms and determinants controlling t...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Toscano, Miguel G, Navarro-Montero, Oscar, Ayllon, Veronica, Ramos-Mejia, Veronica, Guerrero-Carreno, Xiomara, Bueno, Clara, Romero, Tamara, Lamolda, Mar, Cobo, Marien, Martin, Francisco, Menendez, Pablo, Real, Pedro J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426806/
https://ncbi.nlm.nih.gov/pubmed/25292191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.196
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