Alveolar fluid neutrophil elastase activity in the adult respiratory distress syndrome is complexed to alpha-2-macroglobulin.

We characterized the elastase and antielastase activity of the alveolar fluid of seven patients with the adult respiratory distress syndrome (ARDS) and thirteen normal volunteers. Alpha-1-antitrypsin (A1AT) concentrations were 60-fold higher in ARDS as compared to normal lavage fluid (2,140 +/- 498...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Wewers, M D, Herzyk, D J, Gadek, J E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442677/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2459160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113724
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